SCHEMBL1731656

SCHEMBL1731656

CCOc1cc2c(c(F)c1OCC)C(=N)N(CC(=O)c1cc(C(CC)C(=O)O)c(O)c(C(C)(C)C)c1)C2

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2R P25116 17/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28740924 0.90 F2R (0.70) F2R
Bromide SCHEMBL1728973 0.89 F2R (0.71) F2R
SCHEMBL1729720 0.89 F2R (0.69) F2R
Bromide SCHEMBL1730472 0.88 F2R (0.69) F2R
Bromide SCHEMBL1732191 0.86 F2R (0.65) F2R
Bromide SCHEMBL1730765 0.85 F2R (0.71) F2R
SCHEMBL14449044 0.85 F2R (0.71) F2R
Bromide SCHEMBL1731233 0.85 F2R (0.64) F2R
Bromide SCHEMBL5484093 0.85 F2R (0.64) F2R
SCHEMBL14449177 0.85 F2R (0.64) F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391451-B1 2-IMINOPYRROLIDINE DERIVATES EISAI R&D MAN CO LTD (JP) 2011-11-23 EP disclosed