Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 17/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1732426 | 0.99 | F2R (0.43) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730770 | 0.89 | F2R (0.54) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL5487328 | 0.88 | F2R (0.43) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1729940 | 0.87 | F2R (0.45) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731808 | 0.86 | F2R (0.44) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732103 | 0.86 | F2R (0.45) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732156 | 0.85 | F2R (0.43) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1729916 | 0.85 | F2R (0.44) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731020 | 0.84 | F2R (0.41) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL1729083 | 0.84 | F2R (0.52) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |