Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370498 | 0.84 | EPHX1 (0.34) | EPHX1TP53GSRKDM4EGMNN | |
| SCHEMBL3017799 | 0.75 | EPHX2 (0.43) | TP53KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL3715069 | 0.73 | — | — | |
| SCHEMBL27978544 | 0.73 | — | — | |
| SCHEMBL7590908 | 0.72 | — | — | |
| SCHEMBL7596579 | 0.72 | — | — | |
| SCHEMBL7597510 | 0.72 | — | — | |
| SCHEMBL19976650 | 0.69 | EPHX1 (0.45) | EPHX1MAPTSMN1; SMN2 | |
| SCHEMBL7592242 | 0.69 | MEN1 (0.30) | — | |
| SCHEMBL31483805 | 0.68 | EPHX1 (0.36) | EPHX1TP53GSRKDM4EGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151820-A1 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015188085-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. (US) | 2015-12-10 | — | — | WO | disclosed |