Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 8/20 | 0.45 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | KCNJ2 | P63252 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17317738 | 0.87 | KCNK3 (0.42) | KCNK3DPP4DPP8DPP7DPP9 | |
| SCHEMBL17317798 | 0.86 | KCNK3 (0.43) | KCNK3DPP4DPP8DPP7DPP9 | |
| SCHEMBL17317576 | 0.86 | KCNK3 (0.41) | KCNK3DPP4DPP8DPP7DPP9 | |
| Trifluoroacetic Acid SCHEMBL17317782 | 0.84 | KCNK3 (0.40) | KCNK3DPP4DPP8DPP7DPP9 | |
| SCHEMBL17328137 | 0.84 | KCNK3 (0.44) | KCNK3DPP4DPP8DPP7DPP9 | |
| SCHEMBL17317632 | 0.84 | KCNK3 (0.44) | KCNK3DPP4DPP8DPP7DPP9 | |
| SCHEMBL17328194 | 0.84 | KCNK3 (0.44) | KCNK3DPP4DPP8DPP7DPP9 | |
| SCHEMBL17328186 | 0.82 | KCNK3 (0.44) | KCNK3DPP4DPP8DPP7DPP9 | |
| SCHEMBL17317696 | 0.82 | KCNK3 (0.46) | KCNK3DPP4DPP8DPP7DPP9 | |
| SCHEMBL17317858 | 0.82 | KCNK3 (0.50) | KCNK3DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152206-A1 | ATX MODULATING AGENTS | Biogen MA Inc. (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015188051-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. (US) | 2015-12-10 | — | — | WO | disclosed |