Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722464 | 0.87 | GAA (0.79) | GAAPLA2G1BATG4BALDH1A1KMT2A | |
| SCHEMBL14314807 | 0.86 | GAA (0.64) | GAAPLA2G1BATG4BALDH1A1KMT2A | |
| SCHEMBL3461823 | 0.86 | GAA (0.64) | GAAPLA2G1BATG4BALDH1A1KMT2A | |
| SCHEMBL16509641 | 0.82 | RECQL (0.70) | GAAALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL14236894 | 0.82 | GAA (0.68) | GAAPLA2G1BATG4BALDH1A1KMT2A | |
| SCHEMBL8280316 | 0.81 | GAA (0.69) | GAAALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL279948 | 0.80 | GAA (0.70) | GAAPLA2G1BATG4BALDH1A1KMT2A | |
| SCHEMBL17898048 | 0.80 | MEN1 (0.52) | GAAALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL3453484 | 0.79 | GAA (0.68) | GAAPLA2G1BATG4BALDH1A1KMT2A | |
| SCHEMBL6276561 | 0.79 | HPGD (0.54) | GAAKMT2AHPGDMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |