SCHEMBL17319404

SCHEMBL17319404

COn1c(NC(C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(Cl)cc1C)CC2

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRLHR P49683 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435845 1.00 PRLHR (0.85) PRLHR
SCHEMBL436928 0.92 PRLHR (1.00) PRLHR
SCHEMBL450455 0.92 PRLHR (1.00) PRLHR
SCHEMBL437423 0.90 PRLHR (1.00) PRLHR
SCHEMBL435830 0.90 PRLHR (1.00) PRLHR
Hydrochloric Acid SCHEMBL447756 0.89 PRLHR (1.00) PRLHR
SCHEMBL17319403 0.88 PRLHR (1.00) PRLHR
SCHEMBL437382 0.88 PRLHR (1.00) PRLHR
SCHEMBL437437 0.88 PRLHR (1.00) PRLHR
SCHEMBL450489 0.88 PRLHR (1.00) PRLHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9206173-B2 Heterocyclic compounds for the treatment of stress-related conditions OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2015-12-08 US disclosed
US-9206173-B2 Heterocyclic compounds for the treatment of stress-related conditions OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2015-12-08 US disclosed