Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 17/20 | 1.00 |
| ▸ | MEN1 | O00255 | 16/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 1.00 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 1.00 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | PSMD14 | O00487 | 1/20 | 1.00 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.90 |
| ▸ | PTPN12 | Q05209 | 3/20 | 0.90 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.90 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.90 |
| ▸ | RAB9A | P51151 | 1/20 | 0.90 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.90 |
| ▸ | POLB | P06746 | 9/20 | 0.80 |
| ▸ | NPC1 | O15118 | 1/20 | 0.80 |
| ▸ | CTDSP1 | Q9GZU7 | 5/20 | 0.79 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.79 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.79 |
| ▸ | APAF1 | O14727 | 1/20 | 0.73 |
| ▸ | MYC | P01106 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008585 | 1.00 | KMT2A (1.00) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL12008784 | 0.94 | TDP1 (1.00) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL12008780 | 0.90 | KMT2A (0.83) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL12008423 | 0.89 | KMT2A (1.00) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL12008592 | 0.89 | KMT2A (1.00) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL12008605 | 0.89 | KMT2A (1.00) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL17319553 | 0.89 | KMT2A (1.00) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL12008595 | 0.88 | KMT2A (1.00) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL12008569 | 0.88 | KMT2A (1.00) | KMT2AMEN1TDP1SAE1UBA2 | |
| SCHEMBL12008588 | 0.87 | KMT2A (0.76) | KMT2AMEN1TDP1SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206412-B2 | Thioxothiazolidine inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |