Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.62 |
| ▸ | MEN1 | O00255 | 13/20 | 0.62 |
| ▸ | PTPN12 | Q05209 | 3/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.62 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.62 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 7/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | DDX3X | O00571 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008582 | 0.91 | KMT2A (0.75) | MAPTTDP1KMT2AMEN1PTPN12 | |
| SCHEMBL12008583 | 0.80 | KMT2A (0.77) | MAPTTDP1KMT2AMEN1PTPN12 | |
| SCHEMBL12008787 | 0.80 | KMT2A (0.76) | MAPTTDP1KMT2AMEN1PTPN12 | |
| SCHEMBL12008609 | 0.79 | KMT2A (0.82) | TDP1KMT2AMEN1PTPN12GPR35 | |
| SCHEMBL12008805 | 0.79 | KMT2A (0.79) | MAPTTDP1KMT2AMEN1PTPN12 | |
| SCHEMBL12008572 | 0.78 | KMT2A (0.89) | MAPTTDP1KMT2AMEN1PTPN12 | |
| SCHEMBL12008584 | 0.77 | MEN1 (0.87) | MAPTTDP1KMT2AMEN1PTPN12 | |
| SCHEMBL12008586 | 0.77 | MEN1 (1.00) | MAPTTDP1KMT2AMEN1PTPN12 | |
| SCHEMBL12008764 | 0.77 | KMT2A (1.00) | MAPTTDP1KMT2AMEN1PTPN12 | |
| SCHEMBL12008755 | 0.76 | KMT2A (0.86) | MAPTTDP1KMT2AMEN1PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206412-B2 | Thioxothiazolidine inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |