Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
| ▸ | FURIN | P09958 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5487892 | 0.99 | F2R (0.32) | F2RHSD11B1 | |
| Bromide SCHEMBL1732071 | 0.89 | F2R (0.32) | F2RHSD11B1KHKFURIN | |
| Bromide SCHEMBL1732180 | 0.89 | F2R (0.39) | F2RHSD11B1KHKFURIN | |
| Hydrochloric Acid SCHEMBL5488278 | 0.89 | F2R (0.37) | F2RHSD11B1KHKFURIN | |
| Trifluoroacetic Acid SCHEMBL1729408 | 0.86 | F2R (0.37) | F2RKHK | |
| Bromide SCHEMBL1729980 | 0.86 | KHK (0.32) | HSD11B1KHKFURIN | |
| Hydrochloric Acid SCHEMBL1731459 | 0.83 | F2R (0.46) | F2R | |
| Trifluoroacetic Acid SCHEMBL1729482 | 0.81 | F2R (0.46) | F2RKHK | |
| SCHEMBL1729411 | 0.81 | F2R (0.40) | F2RKHK | |
| Bromide SCHEMBL1731605 | 0.81 | F2R (0.40) | F2RHSD11B1KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |