SCHEMBL17320756

SCHEMBL17320756

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccnc5)cc4)c4ccccc34)c3ccc(-c4ccncc4)cc23)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.55
IMPDH2 P12268 1/20 0.45
DHODH Q02127 1/20 0.43
CYP11B1 P15538 3/20 0.42
CYP11B2 P19099 2/20 0.42
CYP19A1 P11511 2/20 0.42
CYP17A1 P05093 1/20 0.42
MKNK1 Q9BUB5 3/20 0.41
CYP1A2 P05177 3/20 0.39
CYP3A4 P08684 2/20 0.39
LMNA P02545 1/20 0.39
RAF1 P04049 1/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39
MKNK2 Q9HBH9 2/20 0.39
TDP2 O95551 1/20 0.39
FLT3 P36888 1/20 0.39
CHEK1 O14757 2/20 0.39
AURKA O14965 1/20 0.39
DAPK3 O43293 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10016745 0.89 CYP2A6 (0.48) PIK3CADHODHCYP11B1CYP11B2CYP19A1
SCHEMBL15977643 0.85 CYP11B1 (0.53) PIK3CADHODHCYP11B1CYP11B2CYP19A1
SCHEMBL17320748 0.85 CYP2A6 (0.50) PIK3CADHODHCYP11B1CYP11B2CYP19A1
SCHEMBL15977675 0.85 CYP11B1 (0.53) PIK3CADHODHCYP11B1CYP11B2CYP19A1
SCHEMBL10030022 0.85 CYP11B1 (0.53) PIK3CADHODHCYP11B1CYP11B2CYP19A1
SCHEMBL10030052 0.85 CYP11B1 (0.53) PIK3CADHODHCYP11B1CYP11B2CYP19A1
SCHEMBL10017017 0.85 NOTUM (0.54) PIK3CAIMPDH2DHODHMKNK1LMNA
SCHEMBL18135377 0.84 PIK3CA (0.50) PIK3CAIMPDH2DHODHCYP11B1CYP11B2
SCHEMBL9613008 0.84 CYP11B1 (0.46) PIK3CADHODHCYP11B1CYP11B2CYP19A1
SCHEMBL10300954 0.83 CYP11B1 (0.54) PIK3CADHODHCYP11B1CYP11B2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10347842-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-09 US disclosed
US-20180138417-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2018-05-17 US disclosed
US-20180138417-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2018-05-17 US disclosed
US-9893289-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-13 US disclosed
US-9893289-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-13 US disclosed
US-20150357574-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-10 US disclosed
US-20150357574-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-10 US disclosed