Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1731915 | 1.00 | F2R (0.44) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731894 | 0.99 | F2R (0.45) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730224 | 0.95 | F2R (0.46) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732078 | 0.94 | F2R (0.47) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730707 | 0.93 | F2R (0.45) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731261 | 0.93 | F2R (0.45) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731425 | 0.92 | F2R (0.41) | F2R | |
| Bromide SCHEMBL1731935 | 0.92 | F2R (0.42) | F2R | |
| Bromide SCHEMBL1728098 | 0.91 | F2R (0.51) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1729991 | 0.91 | F2R (0.43) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240045124-A1 | LAMINATED STRUCTURE FOR SOLAR RADIATION SHIELDING | SUMITOMO METAL MINING CO., LTD. (JP) | 2024-02-08 | — | — | US | disclosed |
| EP-4269097-A1 | LAMINATED STRUCTURE FOR SOLAR RADIATION SHIELDING | SUMITOMO METAL MINING CO., LTD. (JP) | 2023-11-01 | — | — | EP | disclosed |
| EP-3192780-B1 | INTERLAYER FOR LAMINATED GLASS, AND LAMINATED GLASS | SEKISUI CHEMICAL CO LTD (JP) | 2021-01-13 | — | — | EP | disclosed |
| US-10767089-B2 | Thermoplastic polymer composition and molded article | KURARAY CO., LTD. (JP) | 2020-09-08 | — | — | US | disclosed |
| US-10745598-B2 | Thermoplastic polymer composition and molded article | KURARAY CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20200109323-A1 | THERMOPLASTIC POLYMER COMPOSITION AND MOLDED ARTICLE | KURARAY CO., LTD. (JP) | 2020-04-09 | — | — | US | disclosed |
| EP-3360925-B1 | POLYVINYL ACETAL RESIN COMPOSITION, ADHESIVE SHEET, AND METHOD FOR PRODUCING ADHESIVE SHEET | SEKISUI CHEMICAL CO LTD (JP) | 2020-01-29 | — | — | EP | disclosed |
| EP-3006502-B1 | HEAT RAY-SHIELDING MICROPARTICLE-CONTAINING COMPOSITION AND METHOD FOR PRODUCING SAME, HEAT RAY-SHIELDING FILM, AND HEAT RAY-SHIELDING LAMINATED TRANSPARENT BASE MATERIAL | SUMITOMO METAL MINING CO (JP) | 2019-11-20 | — | — | EP | disclosed |
| US-10308801-B2 | Heat ray-shielding particle-containing composition and method of producing the same, heat ray-shielding film, and heat ray-shielding laminated transparent base material | SUMITOMO METAL MINING CO., LTD. (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20170226390-A1 | THERMOPLASTIC POLYMER COMPOSITION AND MOLDED ARTICLE | KURARAY CO., LTD. (JP) | 2017-08-10 | — | — | US | disclosed |
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| EP-1640348-A1 | SUN SCREENING LAMINATED STRUCTURE | SUMITOMO METAL MINING COMPANY LIMITED (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-20060008640-A1 | Laminated structure for shielding against solar radiation | SUMITOMO METAL MINING CO., LTD. (JP) | 2006-01-12 | — | — | US | disclosed |
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| US-6720082-B1 | GLASS PLATE SANDWICHED WITH EITHER ANOTHER GLASS PLATE OR ORGANIC POLYMER FILM BY ORGANIC RESIN LAYER WHICH CONTAINS ETHYLENE-VINYL ACETATE COPOLYMER IN AT LEAST PART OF PERIPHERAL AREA OF PLATE AND POLYVINYL BUTYRAL IN OTHER AREAS | BRIDGESTONE CORPORATION (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1346962-A1 | FILM-REINFORCED GLASSES | BRIDGESTONE CORPORATION (JP) | 2003-09-24 | — | — | EP | disclosed |
| EP-1347069-A1 | HIGH-STRENGTH SPRING STEEL AND SPRING STEEL WIRE | NIPPON STEEL CORPORATION (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-20030111159-A1 | Film-reinforced glasses | BRIDGESTONE CORPORATION (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1228861-A1 | GLASS WITH IMPROVED IMPACT RESISTANCE | BRIDGESTONE CORPORATION (JP) | 2002-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | F2R 2290/4885KDM4E 3161/4885NPC1 4243/4885 |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | F2R 2289/4885KDM4E 3132/4885NPC1 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.