Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5484047 | 0.99 | F2R (0.42) | F2RCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL14449085 | 0.92 | F2R (0.43) | F2RCYP3A4MEN1KMT2AKDM4E | |
| Bromide SCHEMBL1730897 | 0.91 | F2R (0.42) | F2RMEN1KMT2AKDM4EMAPT | |
| Bromide SCHEMBL1729801 | 0.90 | F2R (0.42) | F2RMEN1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1730971 | 0.89 | F2R (0.43) | F2RCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL1729423 | 0.89 | F2R (0.41) | F2RCYP3A4MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5484516 | 0.88 | F2R (0.40) | F2RMEN1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1729216 | 0.88 | F2R (0.40) | F2RCYP3A4KDM4EMAPTRAB9A | |
| SCHEMBL14449067 | 0.88 | F2R (0.45) | F2RCYP3A4MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL1729247 | 0.87 | F2R (0.44) | F2RCYP3A4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |