SCHEMBL1732422

SCHEMBL1732422

CCOc1cc2c(cc1C(=O)NC)/C(=N/C(=O)OC)N(CC(=O)c1cc(N3CCCC3)c(OC(CC)C(=O)O)c(C(C)(C)C)c1)C2

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2R P25116 9/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1731906 1.00 F2R (0.43) F2R
SCHEMBL1729422 0.93 F2R (0.40) F2R
SCHEMBL1729427 0.93 F2R (0.40) F2R
SCHEMBL5482320 0.91 F2R (0.47) F2R
SCHEMBL5482316 0.91 F2R (0.47) F2R
Bromide SCHEMBL1731662 0.88 F2R (0.50) F2R
SCHEMBL14468846 0.85 F2R (0.52) F2R
SCHEMBL5494510 0.84 F2R (0.42) F2R
SCHEMBL5494503 0.84 F2R (0.42) F2R
Hydrochloric Acid SCHEMBL1730069 0.83 F2R (0.51) F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391451-B1 2-IMINOPYRROLIDINE DERIVATES EISAI R&D MAN CO LTD (JP) 2011-11-23 EP disclosed