Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28699226 | 0.91 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BALDH1A1 | |
| Water SCHEMBL27658399 | 0.91 | — | — | |
| Water SCHEMBL176514 | 0.85 | — | — | |
| Water SCHEMBL27967378 | 0.85 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BALDH1A1 | |
| Water SCHEMBL1829896 | 0.85 | — | — | |
| Water SCHEMBL7857556 | 0.85 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BALDH1A1 | |
| Water SCHEMBL5960033 | 0.85 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BALDH1A1 | |
| Water SCHEMBL8752018 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL28977379 | 0.80 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BALDH1A1 | |
| Hydrochloric Acid SCHEMBL10598501 | 0.80 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10823477-B2 | Thermal energy storage member and storage container using the same, and refrigerator using the same | SHARP KABUSHIKI KAISHA (JP) | 2020-11-03 | — | — | US | disclosed |
| US-10179686-B2 | Storage container with heat storage material that provides heat to shelf included in storage container | SHARP KABUSHIKI KAISHA (JP) | 2019-01-15 | — | — | US | disclosed |
| US-20170153054-A1 | COLD INSULATION MEMBER | SHARP KABUSHIKI KAISHA (JP) | 2017-06-01 | — | — | US | disclosed |
| US-20160370084-A1 | THERMAL ENERGY STORAGE MEMBER AND STORAGE CONTAINER USING THE SAME, AND REFRIGERATOR USING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2016-12-22 | — | — | US | disclosed |
| US-20150360842-A1 | STORAGE CONTAINER | SHARP KABUSHIKI KAISHA (JP) | 2015-12-17 | — | — | US | disclosed |