SCHEMBL1733254

SCHEMBL1733254

O=C(OCc1ccccc1)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.73
CYP19A1 P11511 2/20 0.73
RECQL P46063 1/20 0.61
ALDH1A1 P00352 5/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
HPGD P15428 1/20 0.55
KDM4E B2RXH2 1/20 0.52
EPHX2 P34913 3/20 0.52
GAA P10253 2/20 0.51
MAPT P10636 1/20 0.51
XBP1 P17861 1/20 0.51
LMNA P02545 1/20 0.50
HSD11B1 P28845 1/20 0.49
P2RX7 Q99572 1/20 0.49
FAAH O00519 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL7978797 0.94 CYP17A1 (0.66) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL31613300 0.93 CYP17A1 (0.63) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL31538453 0.91 CYP17A1 (0.66) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL18007743 0.89 CYP17A1 (0.59) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL20620855 0.87 CYP17A1 (0.60) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL13148547 0.87 CYP17A1 (0.61) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL22070864 0.86 CYP17A1 (0.56) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL18007735 0.86 CYP17A1 (0.56) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL22070598 0.85 CYP17A1 (0.55) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2
SCHEMBL18007750 0.85 CYP17A1 (0.55) CYP17A1CYP19A1RECQLALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115038697-A Therapeutic agents and methods of treatment 佛罗里达大学研究基金公司 2022-09-09 CN disclosed
EP-0999474-B1 Photoresist resin composition and method for forming a pattern DAICEL CHEM (JP) 2011-11-23 EP disclosed