Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15937435 | 0.93 | JAK3 (0.44) | JAK3BTKMAPTALDH1A1KMT2A | |
| SCHEMBL15937432 | 0.89 | MAPT (0.40) | JAK3BTKMAPTALDH1A1KMT2A | |
| SCHEMBL15937400 | 0.88 | JAK3 (0.42) | JAK3BTKMAPTALDH1A1KMT2A | |
| SCHEMBL15937425 | 0.86 | KMT2A (0.54) | MAPTALDH1A1KMT2AMCL1KDM4E | |
| SCHEMBL17333137 | 0.85 | KMT2A (0.53) | MAPTALDH1A1KMT2AMCL1KDM4E | |
| Acoziborole SCHEMBL1164186 | 0.84 | JAK3 (0.49) | JAK3BTKALDH1A1PTGS1 | |
| SCHEMBL2311479 | 0.84 | JAK3 (0.49) | JAK3BTKMAPTRAB9ANPC1 | |
| Acoziborole SCHEMBL29502840 | 0.84 | JAK3 (0.49) | JAK3BTKALDH1A1PTGS1 | |
| SCHEMBL15937402 | 0.84 | JAK3 (0.48) | JAK3BTKNPSR1L3MBTL1 | |
| SCHEMBL15937389 | 0.84 | KMT2A (0.52) | MAPTALDH1A1KMT2AMCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815857-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-11-14 | — | — | US | claimed |
| US-20170210762-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2017-07-27 | — | — | US | claimed |
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2020-08-06 | — | — | US | disclosed |
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2020-08-06 | — | — | US | disclosed |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2019-05-09 | — | — | US | disclosed |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2019-05-09 | — | — | US | disclosed |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2018-03-08 | — | — | US | disclosed |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2018-03-08 | — | — | US | disclosed |
| US-9815857-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9815857-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170210762-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2017-07-27 | — | — | US | disclosed |
| US-20170210762-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2017-07-27 | — | — | US | disclosed |
| US-9598443-B2 | Boron containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| US-9598443-B2 | Boron containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150361104-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2015-12-17 | — | — | US | disclosed |
| US-20150361104-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | JAK3 3665/4885BTK 68/4885MAPT 3310/4885 |
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | BTD, BAD, BRI3BP | JAK3 3665/4885BTK 68/4885MAPT 3310/4885 |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | JAK3 3665/4885BTK 68/4885MAPT 3310/4885 |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | JAK3 3665/4885BTK 68/4885MAPT 3310/4885 |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | BTD, BAD, BRI3BP | JAK3 3665/4885BTK 68/4885MAPT 3310/4885 |
| US-20150361104-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | JAK3 3665/4885BTK 68/4885MAPT 3310/4885 |
| US-20170210762-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | JAK3 3665/4885BTK 68/4885MAPT 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.