SCHEMBL1733445

SCHEMBL1733445

COC(=O)Oc1ccc(S(=O)(=O)NCCCC(c2ccc(OC)c(OC)c2)N2C(=O)c3cccc(N4CCN(C(C)c5ccccc5)CC4)c3C2=O)o1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 18/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1472902 0.92 UTS2R (0.76) UTS2R
SCHEMBL1472899 0.92 UTS2R (0.76) UTS2R
SCHEMBL1472237 0.88 UTS2R (0.88) UTS2R
SCHEMBL1472243 0.88 UTS2R (0.88) UTS2R
SCHEMBL1472228 0.88 UTS2R (0.88) UTS2R
SCHEMBL1472227 0.88 UTS2R (0.88) UTS2R
SCHEMBL1472076 0.87 UTS2R (1.00) UTS2R
SCHEMBL1472079 0.87 UTS2R (1.00) UTS2R
SCHEMBL1472652 0.87 UTS2R (0.88) UTS2R
SCHEMBL1472879 0.87 UTS2R (0.88) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993554-B1 UROTENSIN II RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA NV (BE) 2011-11-23 EP claimed