SCHEMBL1733494

SCHEMBL1733494

C1CCC1.COc1ccc([C@@H](CCCNC(=O)O)N2C(=O)c3cccc(N4CCN([C@H](C)c5ccccc5)CC4)c3C2=O)cc1OC

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 18/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentane SCHEMBL1734638 1.00 UTS2R (0.83) UTS2R
SCHEMBL9884506 0.93 UTS2R (0.84) UTS2R
SCHEMBL1472360 0.93 UTS2R (0.83) UTS2R
SCHEMBL1472361 0.93 UTS2R (0.83) UTS2R
SCHEMBL1472346 0.92 UTS2R (0.82) UTS2R
SCHEMBL1472906 0.92 UTS2R (0.82) UTS2R
SCHEMBL1472389 0.91 UTS2R (0.81) UTS2R
SCHEMBL1473033 0.91 UTS2R (0.81) UTS2R
SCHEMBL1472235 0.91 UTS2R (0.86) UTS2R
SCHEMBL1472863 0.91 UTS2R (0.81) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993554-B1 UROTENSIN II RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA NV (BE) 2011-11-23 EP claimed