Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 15/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20913194 | 0.81 | AOC3 (0.62) | AOC3KCNH2 | |
| SCHEMBL16053113 | 0.80 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL16053490 | 0.80 | AOC3 (0.78) | AOC3KCNH2 | |
| SCHEMBL16052839 | 0.78 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL30025855 | 0.78 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL16047676 | 0.78 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL16049086 | 0.77 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL30026670 | 0.77 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL30025875 | 0.76 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL16048212 | 0.76 | AOC3 (1.00) | AOC3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386494-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | Benevolentai Cambridge Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098236-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | PROXIMAGEN LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |
| WO-2015189534-A1 | VAP-1 INHIBITORS FOR TREATING MUSCULAR DYSTROPHY | PROXIMAGEN LIMITED (GB) | 2015-12-17 | — | — | WO | disclosed |