Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14742491 | 0.86 | PIK3CD (0.51) | PIK3CDKCNH2PDE4A | |
| SCHEMBL18038541 | 0.86 | PIK3CD (0.51) | PIK3CDKCNH2PDE4A | |
| SCHEMBL14742248 | 0.86 | PIK3CD (0.51) | PIK3CDKCNH2PDE4A | |
| SCHEMBL25642975 | 0.86 | PIK3CD (0.54) | PIK3CDKCNH2PDE4A | |
| SCHEMBL25643004 | 0.86 | PIK3CD (0.54) | PIK3CDKCNH2PDE4A | |
| SCHEMBL17337252 | 0.85 | PIK3CD (0.52) | PIK3CDKCNH2PDE4A | |
| SCHEMBL17333047 | 0.82 | PIK3CD (0.55) | PIK3CDKCNH2PDE4A | |
| SCHEMBL18038542 | 0.81 | PIK3CD (0.47) | PIK3CDKCNH2PDE4A | |
| SCHEMBL18042425 | 0.80 | PIK3CD (0.46) | PIK3CDKCNH2PDE4A | |
| SCHEMBL18038537 | 0.79 | PIK3CD (0.47) | PIK3CDKCNH2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015191677-A1 | BICYCLIC HETEROARYLAMINOALKYL PHENYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2015-12-17 | — | — | WO | disclosed |