Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.44 |
| ▸ | PIK3R2 | O00459 | 10/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15818053 | 0.90 | PIK3R2 (0.40) | PIK3CDPIK3R2PDE10ATDP1 | |
| SCHEMBL17338151 | 0.89 | PIK3CD (0.48) | PIK3CDPIK3R2 | |
| SCHEMBL15817918 | 0.88 | PIK3CD (0.45) | PIK3CDPIK3R2PDE10A | |
| SCHEMBL15818008 | 0.88 | PIK3R2 (0.51) | PIK3CDPIK3R2 | |
| SCHEMBL17338163 | 0.88 | PIK3CD (0.49) | PIK3CDPIK3R2PDE10A | |
| SCHEMBL17338167 | 0.87 | PIK3CD (0.48) | PIK3CDPIK3R2 | |
| SCHEMBL17338164 | 0.86 | PIK3CD (0.48) | PIK3CDPIK3R2PDE10A | |
| SCHEMBL17338226 | 0.86 | PIK3CD (0.52) | PIK3CDPIK3R2 | |
| SCHEMBL17338194 | 0.86 | PIK3CD (0.52) | PIK3CDPIK3R2 | |
| SCHEMBL17338239 | 0.86 | PIK3CD (0.52) | PIK3CDPIK3R2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154958-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015191752-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | disclosed |