Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.70 |
| ▸ | PIK3R2 | O00459 | 15/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17338281 | 1.00 | PIK3CD (0.70) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338272 | 0.95 | PIK3CD (0.69) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338443 | 0.95 | PIK3CD (0.69) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338293 | 0.94 | PIK3CD (0.70) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338407 | 0.94 | PIK3CD (0.70) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338248 | 0.92 | PIK3CD (0.67) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338197 | 0.91 | PIK3CD (0.68) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338247 | 0.87 | PIK3CD (0.71) | PIK3CDPIK3R2 | |
| SCHEMBL17338157 | 0.87 | PIK3CD (0.71) | PIK3CDPIK3R2 | |
| SCHEMBL17338291 | 0.86 | PIK3CD (0.66) | PIK3CDPIK3R2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154958-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | claimed |
| WO-2015191752-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | claimed |