Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.68 |
| ▸ | PIK3R2 | O00459 | 9/20 | 0.62 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17338264 | 0.90 | PIK3CD (0.69) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17338213 | 0.90 | PIK3CD (0.68) | PIK3CDPIK3R2 | |
| SCHEMBL17338299 | 0.85 | PIK3CD (0.66) | PIK3CDPIK3R2 | |
| SCHEMBL17338303 | 0.83 | PIK3CD (0.70) | PIK3CDPIK3R2 | |
| SCHEMBL17338205 | 0.83 | PIK3CD (0.53) | PIK3CDPIK3R2PIK3CGPIK3CA | |
| SCHEMBL17338328 | 0.82 | PIK3CD (0.69) | PIK3CDPIK3R2PIK3CGPIK3CA | |
| SCHEMBL17330632 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CGPIK3CA | |
| SCHEMBL17338342 | 0.81 | PIK3CD (0.68) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17330628 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CGPIK3CA | |
| SCHEMBL15155579 | 0.80 | PIK3CD (0.65) | PIK3CDPIK3R2PIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154958-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | claimed |
| WO-2015191752-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | claimed |