Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213520 | 0.82 | MEN1 (0.40) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL16213419 | 0.81 | MEN1 (0.40) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL16213420 | 0.81 | MEN1 (0.40) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL1734730 | 0.74 | MEN1 (0.47) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL31335359 | 0.74 | KMT2A (0.41) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL30613681 | 0.74 | KMT2A (0.41) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL26132032 | 0.74 | KMT2A (0.41) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL19671101 | 0.74 | MEN1 (0.37) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL21080317 | 0.73 | EPOR (0.46) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL21080314 | 0.73 | EPOR (0.46) | MEN1KMT2ALMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334290-B2 | CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2012-12-18 | — | — | US | disclosed |
| EP-1954287-B1 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110262658-A1 | PROCESS AND DEVICE FOR TREATING THE COATING OF THERMOPLASTIC RESIN CONTAINERS | ZOPPAS MATTEO | 2011-10-27 | — | — | US | disclosed |