Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508861 | 0.89 | CYP2C19 (0.37) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL18932721 | 0.89 | CYP2C19 (0.37) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL18932722 | 0.86 | CYP2C19 (0.44) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL28510350 | 0.86 | CYP2C19 (0.44) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL4029333 | 0.86 | CYP2C19 (0.44) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL17339215 | 0.85 | CYP2C19 (0.34) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL4025300 | 0.82 | CYP2C19 (0.41) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL18932720 | 0.76 | TSHR (0.34) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL18918253 | 0.75 | TSHR (0.40) | CYP2C9TSHRMAPTCYP2C19CYP3A4 | |
| SCHEMBL17339206 | 0.75 | TSHR (0.40) | CYP2C9TSHRMAPTCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10112973-B2 | Process for the preparation of ramipril | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2018-10-30 | — | — | US | disclosed |
| EP-3154940-B1 | PROCESS FOR THE PREPARATION OF RAMIPRIL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-04-18 | — | — | EP | disclosed |
| US-20170158733-A1 | PROCESS FOR THE PREPARATION OF RAMIPRIL | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2017-06-08 | — | — | US | disclosed |
| EP-3154940-A1 | PROCESS FOR THE PREPARATION OF RAMIPRIL | Sanofi-Aventis Deutschland GmbH (DE) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015189108-A1 | PROCESS FOR THE PREPARATION OF RAMIPRIL | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2015-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10112973-B2 | Process for the preparation of ramipril | CYP2S1, CYP3A5, CYP4B1 | CYP2C9 15/4885TSHR 2997/4885MAPT 2318/4885 |
| US-20170158733-A1 | PROCESS FOR THE PREPARATION OF RAMIPRIL | CYP2S1, CYP3A5, CYP4B1 | CYP2C9 15/4885TSHR 2997/4885MAPT 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.