Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 8/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456222 | 1.00 | NPC1L1 (0.51) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL456221 | 1.00 | NPC1L1 (0.51) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL469326 | 1.00 | NPC1L1 (0.51) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL17339709 | 0.94 | NPC1L1 (0.50) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL10070625 | 0.94 | NPC1L1 (0.50) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL454686 | 0.94 | NPC1L1 (0.50) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL454685 | 0.94 | NPC1L1 (0.50) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL455145 | 0.93 | NPC1L1 (0.49) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL469324 | 0.93 | NPC1L1 (0.49) | NPC1L1CNR1ABCB11LMNAPGR | |
| SCHEMBL455144 | 0.93 | NPC1L1 (0.49) | NPC1L1CNR1ABCB11LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212175-B2 | Pharmaceutical hypocholesterolemic compositions | LIPIDEON BIOTECHNOLOGY AG (CH) | 2015-12-15 | — | — | US | disclosed |