Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 3/20 | 0.34 |
| ▸ | ETV6 | P41212 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 3/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127092 | 0.82 | PARP1 (0.43) | CA1CA2CA7CA13CCNA2 | |
| SCHEMBL10126528 | 0.75 | MAPT (0.43) | CA1CA2CA7 | |
| SCHEMBL10127090 | 0.74 | CA1 (0.48) | CA1CA2CA7CA13CCNA2 | |
| SCHEMBL328277 | 0.74 | CNR2 (0.43) | MEN1KMT2A | |
| SCHEMBL10126533 | 0.73 | CA1 (0.44) | CA1CA2CA7CA13CDK2 | |
| SCHEMBL328295 | 0.73 | CA1 (0.44) | CA1CA2CA7CA13PPARG | |
| SCHEMBL10126491 | 0.73 | CA1 (0.41) | CA1CA2CA7CA13PPARG | |
| SCHEMBL10126505 | 0.73 | PTK6 (0.45) | — | |
| SCHEMBL10126599 | 0.73 | CNR2 (0.43) | SYK | |
| SCHEMBL10157042 | 0.73 | MCOLN3 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428508-B1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC (JP) | 2015-12-16 | — | — | EP | disclosed |