Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242009 | 0.93 | ANO1 (0.46) | ANO1RCE1CNR2BCHECNR1 | |
| SCHEMBL1919008 | 0.86 | CYP3A4 (0.50) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL17340642 | 0.83 | CYP3A4 (0.42) | ANO1CYP3A4CYP2C8KCNH2 | |
| SCHEMBL1919204 | 0.83 | CYP3A4 (0.53) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL1918773 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL1918978 | 0.81 | CYP2C8 (0.53) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL10241927 | 0.79 | CYP3A4 (0.50) | ANO1RCE1CNR2BCHECNR1 | |
| SCHEMBL1919864 | 0.78 | CYP3A4 (0.52) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL10241997 | 0.78 | CYP3A4 (0.49) | ANO1CYP3A4CYP2C8KCNH2 | |
| SCHEMBL10242011 | 0.78 | CYP2C8 (0.49) | CYP3A4CYP2C8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326633-B1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2015-12-16 | — | — | EP | disclosed |