SCHEMBL17343385

SCHEMBL17343385

c1ccc(-c2cccc(-c3cc(-c4cccc(-c5ccccc5)c4)nc(-c4cc(-c5cccc6cnccc56)cc(-c5cccc6cnccc56)c4)n3)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.50
KDM4E B2RXH2 4/20 0.43
LMNA P02545 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.43
HPGD P15428 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
IKBKE Q14164 1/20 0.42
TBK1 Q9UHD2 1/20 0.42
SERPINE1 P05121 1/20 0.41
CYP19A1 P11511 1/20 0.41
GLA P06280 1/20 0.40
HASPIN Q8TF76 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAPKAPK2 P49137 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17343351 0.94 TNF (0.53) TNFKDM4ELMNAALDH1A1MAPT
SCHEMBL17343262 0.92 TNF (0.53) TNFKDM4ELMNAALDH1A1MAPT
SCHEMBL17343440 0.90 CYP19A1 (0.53) TNFKDM4ELMNAIKBKETBK1
SCHEMBL17343224 0.89 TNF (0.55) TNFKDM4ELMNAALDH1A1MAPT
SCHEMBL17343365 0.88 PIK3CD (0.48) TNFKDM4ELMNAIKBKETBK1
SCHEMBL24403750 0.87 CYP11B1 (0.51) TNFKDM4ELMNAALDH1A1MAPT
SCHEMBL17343292 0.86 TNF (0.50) TNFKDM4ELMNAALDH1A1MAPT
SCHEMBL17343369 0.86 TNF (0.49) TNFKDM4ELMNAALDH1A1MAPT
SCHEMBL17944848 0.86 TNF (0.56) TNFKDM4ELMNAALDH1A1MAPT
SCHEMBL17720981 0.85 TNF (0.55) TNFKDM4ELMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9680108-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-13 US disclosed
US-9680108-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-13 US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed
US-20160020404-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 US disclosed
US-20160020404-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 US disclosed
US-20150364693-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-17 US disclosed
US-20150364693-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-17 US disclosed