Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345494 | 1.00 | STAT3 (0.48) | STAT3ALDH1A1ELANEMAPTAPAF1 | |
| SCHEMBL18807117 | 0.90 | STAT3 (0.50) | STAT3ALDH1A1MAPTAPAF1MITF | |
| SCHEMBL17345471 | 0.89 | STAT3 (0.52) | STAT3ALDH1A1MAPTAPAF1MITF | |
| SCHEMBL17345495 | 0.89 | STAT3 (0.49) | STAT3ALDH1A1MAPTAPAF1MITF | |
| SCHEMBL17345490 | 0.89 | STAT3 (0.46) | STAT3ALDH1A1MAPTAPAF1MITF | |
| SCHEMBL17345465 | 0.88 | STAT3 (0.50) | STAT3ALDH1A1MAPTAPAF1MITF | |
| SCHEMBL18731409 | 0.87 | STAT3 (0.49) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18731408 | 0.87 | STAT3 (0.49) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL20305843 | 0.86 | STAT3 (0.48) | STAT3ALDH1A1ELANEMAPTAPAF1 | |
| SCHEMBL18731248 | 0.86 | STAT3 (0.45) | STAT3ALDH1A1MAPTAPAF1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153508-A1 | NOVEL ANTICANCER AGENT | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015190489-A1 | NOVEL ANTICANCER AGENT | 京都薬品工業株式会社 | 2015-12-17 | — | — | WO | disclosed |