Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.81 |
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.69 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17951269 | 0.91 | TLR8 (0.88) | TLR8TLR7NUDT1 | |
| SCHEMBL13999937 | 0.90 | TLR8 (0.86) | TLR8TLR7NUDT1 | |
| SCHEMBL28807387 | 0.90 | TLR8 (0.75) | TLR8TLR7NUDT1 | |
| SCHEMBL5111244 | 0.89 | TLR8 (1.00) | TLR8TLR7NUDT1 | |
| SCHEMBL6105673 | 0.89 | TLR8 (0.81) | TLR8TLR7NUDT1 | |
| SCHEMBL15441707 | 0.88 | TLR8 (0.83) | TLR8TLR7NUDT1 | |
| SCHEMBL25697382 | 0.88 | TLR8 (0.78) | TLR8TLR7NUDT1 | |
| SCHEMBL1616206 | 0.87 | TLR8 (0.84) | TLR8TLR7NUDT1 | |
| SCHEMBL6098914 | 0.87 | TLR8 (0.77) | TLR8TLR7NUDT1 | |
| SCHEMBL15318536 | 0.87 | TLR8 (0.80) | TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480253-A1 | ADSORPTION OF IMMUNOPOTENTIATORS TO INSOLUBLE METAL SALTS | Novartis AG (CH) | 2012-08-01 | — | — | EP | disclosed |
| WO-2012031140-A1 | ADSORPTION OF IMMUNOPOTENTIATORS TO INSOLUBLE METAL SALTS | NOVARTIS AG (CH) | 2012-03-08 | — | — | WO | disclosed |