SCHEMBL17348787

SCHEMBL17348787

Bc1ccc2c(c1)c1ncccc1n2-c1cccc(-c2nc(-c3ccccc3)cc(-c3ccccc3)n2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 6/20 0.37
KMT2A Q03164 6/20 0.36
MEN1 O00255 5/20 0.36
ALDH1A1 P00352 5/20 0.36
MAPT P10636 4/20 0.36
HPGD P15428 3/20 0.36
LMNA P02545 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GRM5 P41594 4/20 0.32
PDE4A P27815 2/20 0.32
PDE4C Q08493 2/20 0.32
PDE4D Q08499 2/20 0.32
NTSR1 P30989 1/20 0.32
GLA P06280 1/20 0.32
TSHR P16473 2/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
ALOX12 P18054 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17348783 0.93 ABCG2 (0.33) TOP1KMT2AALDH1A1KDM4EGRM5
SCHEMBL17349626 0.87 TOP1 (0.37) TOP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL18958778 0.86 KDM4E (0.38) TOP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL17349332 0.86 KDM4E (0.38) TOP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL18958446 0.84 KDM4E (0.37) TOP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL18958845 0.84 KDM4E (0.37) TOP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL17348606 0.84 TOP1 (0.36) TOP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL17349176 0.83 KMT2A (0.38) TOP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL17349337 0.83 KMT2A (0.38) TOP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL18958628 0.82 TOP1 (0.36) TOP1KMT2AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015190867-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2015-12-17 WO disclosed