SCHEMBL17349136

SCHEMBL17349136

c1ccc(-n2c3cnccc3c3cccc(-c4ccc5c6ccccc6n(-c6ccc7ccccc7c6)c5c4)c32)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 11/20 0.38
MAPK9 P45984 9/20 0.38
CDK4 P11802 1/20 0.37
CDK6 Q00534 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPK8 P45983 1/20 0.36
DYRK1A Q13627 2/20 0.35
GSK3B P49841 1/20 0.35
KCNH2 Q12809 1/20 0.35
CYP17A1 P05093 1/20 0.34
CYP1A2 P05177 1/20 0.34
TNF P01375 1/20 0.34
CCNC P24863 2/20 0.34
CDK8 P49336 2/20 0.34
F2 P00734 1/20 0.34
F10 P00742 1/20 0.34
PRSS1 P07477 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18958097 1.00 MAPK10 (0.38) MAPK10MAPK9CDK4CDK6KDM4E
SCHEMBL17349279 0.94 MAPK10 (0.38) MAPK10MAPK9KDM4EATML3MBTL1
SCHEMBL18958111 0.94 MAPK10 (0.38) MAPK10MAPK9KDM4EATML3MBTL1
SCHEMBL18958209 0.94 KDM4E (0.37) MAPK10MAPK9CDK4CDK6KDM4E
SCHEMBL17348780 0.94 KDM4E (0.37) MAPK10MAPK9CDK4CDK6KDM4E
SCHEMBL18958092 0.92 KDM4E (0.44) CDK4CDK6KDM4EATML3MBTL1
SCHEMBL17349281 0.92 KDM4E (0.44) CDK4CDK6KDM4EATML3MBTL1
SCHEMBL20149462 0.92 KDM4E (0.44) MAPK10MAPK9KDM4EATML3MBTL1
SCHEMBL20149460 0.92 KDM4E (0.44) MAPK10MAPK9KDM4EATML3MBTL1
SCHEMBL17348728 0.91 CDK4 (0.38) MAPK10MAPK9CDK4CDK6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210257558-A1 Compound For Organic Electronic Element, Organic Electronic Element Using Same, And Electronic Device Thereof DUK SAN NEOLUX CO., LTD (KR) 2021-08-19 US disclosed
US-20210074926-A1 Compound For Organic Electronic Element, Organic Electronic Element Using Same, And Electronic Device Thereof DUK SAN NEOLUX CO LTD (KR) 2021-03-11 US disclosed
US-20200194687-A1 Compound For Organic Electronic Element, Organic Electronic Element Using Same, And Electronic Device Thereof DUK SAN NEOLUX CO LTD (KR) 2020-06-18 US disclosed
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD (KR) 2017-06-15 US disclosed
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD (KR) 2017-06-15 US disclosed
WO-2015190867-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200194687-A1 Compound For Organic Electronic Element, Organic Electronic Element Using Same, And Electronic Device Thereof OR10J3, OR51E2, ETV6 MAPK10 2991/4885MAPK9 1502/4885CDK4 1469/4885
US-20210074926-A1 Compound For Organic Electronic Element, Organic Electronic Element Using Same, And Electronic Device Thereof OR10J3, OR51E2, ETV6 MAPK10 2991/4885MAPK9 1502/4885CDK4 1469/4885
US-20210257558-A1 Compound For Organic Electronic Element, Organic Electronic Element Using Same, And Electronic Device Thereof OR10J3, OR51E2, ETV6 MAPK10 2991/4885MAPK9 1502/4885CDK4 1469/4885
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF OR10J3, OR51E2, ETV6 MAPK10 2991/4885MAPK9 1502/4885CDK4 1469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.