Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966570 | 1.00 | PREP (0.63) | PREPNPSR1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL10476852 | 0.90 | PREP (0.62) | PREPNPSR1TSHRL3MBTL1POLB | |
| SCHEMBL19258206 | 0.88 | PREP (0.71) | PREPNPSR1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL17469366 | 0.88 | PREP (0.71) | PREPNPSR1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL17469372 | 0.88 | PREP (0.71) | PREPNPSR1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL17469393 | 0.88 | PREP (0.71) | PREPNPSR1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL115971 | 0.87 | POLB (0.64) | PREPNPSR1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL13092036 | 0.87 | POLB (0.64) | PREPNPSR1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL1448027 | 0.87 | POLB (0.64) | PREPNPSR1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL636507 | 0.87 | POLB (0.64) | PREPNPSR1ALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957555-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2015-12-23 | — | — | EP | disclosed |