Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.67 |
| ▸ | BAK1 | Q16611 | 7/20 | 0.67 |
| ▸ | BCL2L1 | Q07817 | 15/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22169036 | 0.86 | BCL2 (0.72) | BCL2BAK1BCL2L1 | |
| SCHEMBL20778266 | 0.84 | BCL2 (0.70) | BCL2BAK1BCL2L1 | |
| SCHEMBL30688260 | 0.84 | BCL2 (0.70) | BCL2BAK1BCL2L1 | |
| SCHEMBL1743631 | 0.84 | BCL2 (0.68) | BCL2BAK1BCL2L1 | |
| SCHEMBL1741405 | 0.83 | BCL2 (0.71) | BCL2BAK1BCL2L1 | |
| SCHEMBL29846744 | 0.83 | BCL2 (0.71) | BCL2BAK1BCL2L1 | |
| SCHEMBL19014647 | 0.82 | BCL2 (0.64) | BCL2BAK1BCL2L1 | |
| SCHEMBL17350459 | 0.81 | BCL2 (0.84) | BCL2BAK1BCL2L1 | |
| SCHEMBL376922 | 0.80 | BCL2 (0.64) | BCL2BAK1BCL2L1 | |
| SCHEMBL19308887 | 0.80 | BCL2 (0.78) | BCL2BAK1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957558-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | AbbVie Inc. (US) | 2015-12-23 | — | — | EP | claimed |