Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060324 | 1.00 | AR (1.00) | ARPOLBGAAALDH1A1CYP19A1 | |
| SCHEMBL31060632 | 0.86 | AR (1.00) | ARPOLBGAAALDH1A1CYP19A1 | |
| SCHEMBL21963833 | 0.85 | AR (0.74) | ARPOLBGAAALDH1A1CYP19A1 | |
| SCHEMBL13721646 | 0.85 | AR (0.74) | ARPOLBGAAALDH1A1CYP19A1 | |
| SCHEMBL17354620 | 0.83 | AR (0.70) | ARPOLBGAAALDH1A1CYP19A1 | |
| SCHEMBL16167721 | 0.82 | AR (0.70) | ARGAAALDH1A1CYP19A1 | |
| SCHEMBL2614475 | 0.82 | AR (0.69) | ARALDH1A1KDM4EUSP2IMPDH2 | |
| SCHEMBL1608900 | 0.82 | AR (0.69) | ARPOLBGAAALDH1A1KDM4E | |
| SCHEMBL17354621 | 0.81 | AR (0.68) | ARALDH1A1CYP19A1KDM4E | |
| SCHEMBL4178171 | 0.80 | AR (1.00) | ARPOLBGAACYP19A1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216967-B2 | Imidazolidinedione derivatives | AUTIFONY THERAPEUTICS LIMITED (GB) | 2015-12-22 | — | — | US | disclosed |