Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 16/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827740 | 0.84 | MAPT (0.46) | GPBAR1TACR1 | |
| SCHEMBL14907222 | 0.74 | SIRT3 (0.61) | SIRT3TDP1GPBAR1HSD17B1TACR1 | |
| SCHEMBL15563693 | 0.73 | SIRT3 (0.59) | SIRT3TDP1GPBAR1HSD17B1TACR1 | |
| SCHEMBL4204404 | 0.71 | HCAR2 (0.50) | TP53 | |
| SCHEMBL3827033 | 0.69 | MAPT (0.42) | TP53GPBAR1TACR1 | |
| SCHEMBL24941110 | 0.69 | SIRT3 (0.54) | SIRT3TDP1GPBAR1HSD17B1TACR1 | |
| SCHEMBL17157497 | 0.69 | SIRT3 (0.54) | SIRT3TDP1GPBAR1HSD17B1TACR1 | |
| SCHEMBL21227703 | 0.69 | SIRT3 (0.54) | SIRT3TDP1GPBAR1HSD17B1TACR1 | |
| SCHEMBL4341033 | 0.69 | SIRT3 (0.46) | SIRT3TDP1GPBAR1TACR1 | |
| SCHEMBL16931058 | 0.67 | SIRT3 (0.51) | SIRT3TDP1TP53GPBAR1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963451-B2 | Fused ring pyrimidine compound and pest control agent containing the same | MITSUI CHEMICALS AGRO, INC. (JP) | 2018-05-08 | — | — | US | disclosed |
| US-20150368249-A1 | FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368249-A1 | FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME | CBR3, HRH2, HRH4 | SIRT3 1776/4885TDP1 833/4885TP53 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.