Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.86 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.80 |
| ▸ | PTGFR | P43088 | 2/20 | 0.80 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.80 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.80 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.80 |
| ▸ | PTGIR | P43119 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735816 | 0.93 | PTGER4 (1.00) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1734977 | 0.92 | PTGER4 (1.00) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1736029 | 0.91 | PTGER4 (0.85) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1735045 | 0.91 | PTGER4 (1.00) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1734997 | 0.91 | PTGER4 (1.00) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1735894 | 0.90 | PTGER4 (1.00) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1736153 | 0.90 | PTGER4 (1.00) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1737239 | 0.90 | PTGER4 (1.00) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1736015 | 0.89 | PTGER4 (0.86) | PTGER4TBXA2RPTGFRPTGER3PTGER2 | |
| SCHEMBL1735764 | 0.89 | PTGER4 (0.86) | PTGER4TBXA2RPTGFRPTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885722-B1 | QUINOLINE DERIVATIVES AS EP4 ANTAGONISTS | MERCK CANADA INC (CA) | 2011-11-16 | — | — | EP | claimed |
| US-20110262430-A1 | NOVEL ANTIBODIES | ELLIS JONATHAN HENRY | 2011-10-27 | — | — | US | claimed |