SCHEMBL17360441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17360239	0.90	NTRK1 (0.70)	NTRK1CDK8CDK7CDK6KDR
	SCHEMBL17360359	0.88	NTRK1 (0.60)	NTRK1CDK8CDK7CDK6KDR
	SCHEMBL17360292	0.88	NTRK1 (0.77)	NTRK1CDK8CDK7CDK6KDR
	SCHEMBL17360114	0.87	NTRK1 (0.78)	NTRK1KDRPDGFRB
	SCHEMBL15989451	0.87	NTRK1 (0.63)	NTRK1KDRPDGFRB
	SCHEMBL15989429	0.85	NTRK1 (0.84)	NTRK1
	SCHEMBL15989452	0.85	NTRK1 (0.61)	NTRK1CDK8CDK7CDK6KDR
	SCHEMBL15989459	0.84	NTRK1 (0.62)	NTRK1CDK8CDK7CDK6KDR
	SCHEMBL17360334	0.82	NTRK1 (0.82)	NTRK1
	SCHEMBL17360096	0.81	NTRK1 (0.75)	NTRK1KDRBRAFMAPK14TNNI3K

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.