Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732052 | 0.92 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL17360744 | 0.90 | KCNJ1 (0.69) | KCNJ1KCNH2 | |
| SCHEMBL4549660 | 0.87 | KCNJ1 (0.83) | KCNJ1KCNH2 | |
| SCHEMBL10233873 | 0.86 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL14782904 | 0.85 | KCNJ1 (0.83) | KCNJ1KCNH2 | |
| SCHEMBL10233614 | 0.84 | KCNJ1 (0.84) | KCNJ1KCNH2 | |
| SCHEMBL2730883 | 0.84 | KCNJ1 (0.75) | KCNJ1KCNH2 | |
| SCHEMBL10233969 | 0.84 | KCNJ1 (0.75) | KCNJ1KCNH2 | |
| SCHEMBL2733455 | 0.84 | KCNJ1 (0.93) | KCNJ1KCNH2 | |
| SCHEMBL10234063 | 0.84 | KCNJ1 (1.00) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632465-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2015-12-30 | — | — | EP | disclosed |