Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 20/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368274 | 0.95 | MKNK2 (1.00) | MKNK2 | |
| Trifluoroacetic Acid SCHEMBL2403950 | 0.94 | MKNK2 (0.89) | MKNK2 | |
| Trifluoroacetic Acid SCHEMBL14762927 | 0.91 | MKNK2 (0.74) | MKNK2 | |
| SCHEMBL12274481 | 0.88 | MKNK2 (1.00) | MKNK2 | |
| SCHEMBL12274638 | 0.88 | MKNK2 (1.00) | MKNK2 | |
| Trifluoroacetic Acid SCHEMBL2405069 | 0.87 | MKNK2 (0.91) | MKNK2 | |
| SCHEMBL2369112 | 0.85 | MKNK2 (1.00) | MKNK2 | |
| SCHEMBL17360795 | 0.84 | MKNK2 (0.80) | MKNK2 | |
| SCHEMBL2368299 | 0.84 | MKNK2 (0.85) | MKNK2 | |
| SCHEMBL2408664 | 0.84 | MKNK2 (1.00) | MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539343-B1 | THIENOPYRIMIDINES CONTAINING A SUBSTITUTED ALKYL GROUP FOR PHARMACEUTICAL COMPOSITIONS | EVOTEC INTERNAT GMBH (DE) | 2015-12-30 | — | — | EP | disclosed |