Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736249 | 0.99 | MAPT (0.42) | MAPTDYRK1ATP53CYP1A2CYP3A4 | |
| SCHEMBL1738968 | 0.96 | MAPT (0.41) | MAPTDYRK1ATP53CYP1A2CYP3A4 | |
| SCHEMBL1737416 | 0.96 | MAPT (0.41) | MAPTDYRK1ATP53CYP1A2CYP3A4 | |
| SCHEMBL1738711 | 0.95 | MAPT (0.41) | MAPTDYRK1ATP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1737020 | 0.95 | MAPT (0.40) | MAPTDYRK1ATP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1736162 | 0.95 | MAPT (0.40) | MAPTDYRK1ATP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1736702 | 0.94 | MAPT (0.40) | MAPTDYRK1ATP53CYP1A2CYP3A4 | |
| SCHEMBL1735940 | 0.94 | DYRK1A (0.47) | MAPTDYRK1ATP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1736586 | 0.93 | DYRK1A (0.47) | MAPTDYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1737594 | 0.91 | HRH3 (0.41) | MAPTDYRK1ATP53MCL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |