Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 16/20 | 0.71 |
| ▸ | MKNK1 | Q9BUB5 | 13/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17362516 | 0.91 | MKNK2 (0.72) | MKNK2MKNK1 | |
| SCHEMBL17362629 | 0.87 | MKNK2 (0.66) | MKNK2MKNK1 | |
| SCHEMBL17362686 | 0.87 | MKNK2 (0.66) | MKNK2MKNK1 | |
| SCHEMBL17362847 | 0.86 | MKNK2 (0.65) | MKNK2MKNK1 | |
| SCHEMBL17362977 | 0.86 | MKNK2 (0.65) | MKNK2MKNK1 | |
| SCHEMBL20010877 | 0.85 | MKNK2 (0.64) | MKNK2MKNK1 | |
| SCHEMBL17362723 | 0.84 | MKNK2 (0.63) | MKNK2MKNK1 | |
| SCHEMBL17362950 | 0.84 | MKNK2 (0.63) | MKNK2MKNK1 | |
| SCHEMBL17369312 | 0.83 | MKNK2 (0.82) | MKNK2MKNK1 | |
| SCHEMBL18863088 | 0.83 | MKNK2 (0.74) | MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381232-A1 | METHODS AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2023-11-30 | — | — | US | disclosed |
| US-20230381232-A1 | METHODS AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2023-11-30 | — | — | US | disclosed |
| EP-3521289-B1 | MNK INHIBITORS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-3521289-B1 | MNK INHIBITORS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2023-10-25 | — | — | EP | disclosed |
| US-11564947-B2 | Methods and compositions for cellular immunotherapy | Effector Therapeutics Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| CN-110183449-B | Mnk inhibitors and methods related thereto | 效应治疗股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| US-20210338673-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2021-11-04 | — | — | US | disclosed |
| US-20210338673-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2021-11-04 | — | — | US | disclosed |
| US-20210177898-A1 | METHODS AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2021-06-17 | — | — | US | disclosed |
| US-20210046074-A1 | INHIBITORS OF IMMUNE CHECKPOINT MODULATORS AND RELATED METHODS | EFFECTOR THERAPEUTICS INC (US) | 2021-02-18 | — | — | US | disclosed |
| WO-2016172010-A1 | INHIBITORS OF IMMUNE CHECKPOINT MODULATORS FOR USE IN TREATING CANCER AND INFECTIONS | EFFECTOR THERAPEUTICS, INC. (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160303124-A1 | INHIBITORS OF IMMUNE CHECKPOINT MODULATORS AND RELATED METHODS | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2016-10-20 | — | — | US | disclosed |
| US-20160303124-A1 | INHIBITORS OF IMMUNE CHECKPOINT MODULATORS AND RELATED METHODS | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2016-10-20 | — | — | US | disclosed |
| US-9382248-B2 | Mnk inhibitors and methods related thereto | EFFECTOR THERAPEUTICS, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-9382248-B2 | Mnk inhibitors and methods related thereto | EFFECTOR THERAPEUTICS, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-9382248-B2 | Mnk inhibitors and methods related thereto | EFFECTOR THERAPEUTICS, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150376181-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-12-31 | — | — | US | disclosed |
| US-20150376181-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-12-31 | — | — | US | disclosed |
| US-20150376181-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-12-31 | — | — | US | disclosed |
| WO-2015200481-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS, INC. (US) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376181-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | TNNI3K, NIM1K, NEK9 | MKNK2 83/4885MKNK1 75/4885 |
| US-11564947-B2 | Methods and compositions for cellular immunotherapy | PBK, CD4, LY6K | MKNK2 21/4885MKNK1 40/4885 |
| US-20160303124-A1 | INHIBITORS OF IMMUNE CHECKPOINT MODULATORS AND RELATED METHODS | PDCD10, CD274, PDCD1LG2 | MKNK2 184/4885MKNK1 59/4885 |
| US-20230381232-A1 | METHODS AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY | PBK, CD4, LY6K | MKNK2 21/4885MKNK1 40/4885 |
| US-20210177898-A1 | METHODS AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY | PBK, CD4, LY6K | MKNK2 21/4885MKNK1 40/4885 |
| US-20210046074-A1 | INHIBITORS OF IMMUNE CHECKPOINT MODULATORS AND RELATED METHODS | PDCD10, CD274, PDCD1LG2 | MKNK2 184/4885MKNK1 59/4885 |
| US-20210338673-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | TNNI3K, NIM1K, NEK9 | MKNK2 83/4885MKNK1 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.