Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 17/20 | 0.78 |
| ▸ | CLK2 | P49760 | 14/20 | 0.78 |
| ▸ | CLK3 | P49761 | 14/20 | 0.78 |
| ▸ | WNT1 | P04628 | 12/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14792504 | 0.92 | DYRK1A (0.78) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL14792146 | 0.92 | DYRK1A (0.83) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL17364521 | 0.92 | DYRK1A (0.82) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL17364525 | 0.92 | DYRK1A (0.83) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL14792443 | 0.91 | DYRK1A (0.93) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL14804268 | 0.91 | DYRK1A (0.84) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL15473301 | 0.91 | DYRK1A (0.85) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL14792433 | 0.90 | DYRK1A (0.90) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL14792771 | 0.90 | DYRK1A (0.82) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL14785601 | 0.90 | DYRK1A (0.93) | DYRK1ACLK2CLK3WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221793-B2 | Indazole-3-carboxamides and their use as Wnt/β-catenin signaling pathway inhibitors | SAMUMED, LLC (US) | 2015-12-29 | — | — | US | disclosed |