SCHEMBL17366152

SCHEMBL17366152

O=C1c2ccccc2[C@@](OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc(Br)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 20/20 1.00
TP53 P04637 6/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2459482 1.00 MDM2 (1.00) MDM2TP53
SCHEMBL2455570 0.95 MDM2 (1.00) MDM2TP53
SCHEMBL2455050 0.91 MDM2 (1.00) MDM2TP53
SCHEMBL7986408 0.91 MDM2 (1.00) MDM2TP53
SCHEMBL7991694 0.91 MDM2 (1.00) MDM2TP53
SCHEMBL21539929 0.91 MDM2 (0.91) MDM2TP53
SCHEMBL2456515 0.91 MDM2 (1.00) MDM2TP53
SCHEMBL2453990 0.91 MDM2 (1.00) MDM2TP53
SCHEMBL2457602 0.91 MDM2 (1.00) MDM2TP53
SCHEMBL7986241 0.91 MDM2 (1.00) MDM2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2960233-A1 NEW THERAPEUTIC AGENTS Cancer Research Technology Limited (GB) 2015-12-30 EP disclosed