Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 8/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366153 | 0.86 | MDM2 (0.52) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL17366148 | 0.81 | CYP2C9 (0.57) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL17366184 | 0.79 | MDM2 (0.46) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL17366164 | 0.77 | MDM2 (0.53) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL17366183 | 0.77 | MDM2 (0.53) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL17366182 | 0.75 | MDM2 (0.56) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL12332978 | 0.75 | MDM2 (0.53) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL17366176 | 0.75 | MDM2 (0.53) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL17366163 | 0.75 | MDM2 (0.56) | MEN1KMT2AMDM2CYP2C9CYP2C19 | |
| SCHEMBL17366165 | 0.75 | MDM2 (0.55) | MEN1KMT2AMDM2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960233-A1 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2015-12-30 | — | — | EP | disclosed |