Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047256 | 0.85 | NSD2 (0.45) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL15806741 | 0.82 | EGFR (0.42) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL1509936 | 0.80 | NQO1 (0.50) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL7912630 | 0.78 | NSD2 (0.46) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL25299247 | 0.78 | NSD2 (0.46) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL2171833 | 0.77 | EGFR (0.43) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL1777505 | 0.77 | NSD2 (0.45) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL23414843 | 0.77 | KDM4E (0.45) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL15300658 | 0.77 | NSD2 (0.45) | NSD2NSD3SLC6A4EGFRKDR | |
| SCHEMBL29972592 | 0.77 | KDM4E (0.45) | NSD2NSD3SLC6A4EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |