Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 3/20 | 0.68 |
| ▸ | PGR | P06401 | 3/20 | 0.68 |
| ▸ | ESR1 | P03372 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.67 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.67 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.67 |
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424986 | 0.99 | NR1I2 (0.68) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL17424956 | 0.92 | NR1I2 (0.67) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL16092895 | 0.92 | NR1I2 (0.81) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL9871538 | 0.91 | NR1I2 (0.72) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL9871550 | 0.91 | NR1I2 (0.72) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL15100211 | 0.90 | NR1I2 (0.72) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL17122849 | 0.90 | NR1I2 (0.72) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL9039954 | 0.90 | NR1I2 (0.72) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL9039966 | 0.90 | NR1I2 (0.72) | NR1I2HTR2CPPARGPGRESR1 | |
| SCHEMBL15100223 | 0.90 | NR1I2 (0.72) | NR1I2HTR2CPPARGPGRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190115-A1 | SALT OF CEPHALOSPORIN DERIVATIVE, CRYSTALLINE SOLID FORM OF SAME AND METHOD FOR PRODUCING SAME | Shionogi & Co., Ltd. (JP) | 2017-07-12 | — | — | EP | disclosed |
| EP-2960244-B1 | CEPHALOSPORIN HAVING CATECHOL GROUP | SHIONOGI & CO (JP) | 2016-09-14 | — | — | EP | disclosed |
| EP-2341053-B1 | CEPHALOSPORIN HAVING CATECHOL GROUP | SHIONOGI & CO (JP) | 2016-01-13 | — | — | EP | disclosed |
| EP-2960244-A1 | CEPHALOSPORIN HAVING CATECHOL GROUP | Shionogi&Co., Ltd. (JP) | 2015-12-30 | — | — | EP | disclosed |