SCHEMBL17366386

SCHEMBL17366386

Cc1ccc(C(c2ccc(N=C=O)cc2)c2ccc(N=C=O)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.45
TSHR P16473 2/20 0.45
TRPA1 O75762 1/20 0.44
TDP1 Q9NUW8 3/20 0.38
MAPK1 P28482 2/20 0.38
GAA P10253 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CHRNA7 P36544 1/20 0.34
CYP1A2 P05177 1/20 0.34
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
STAT3 P40763 1/20 0.33
STAT1 P42224 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR3E A5X5Y0 1/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
SLC22A3 O75751 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL93536 0.89 CYP3A4 (0.54) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL93286 0.87 CYP3A4 (0.56) CYP3A4TSHRTRPA1TDP1MAPK1
Hydrogen Sulfide SCHEMBL27351182 0.85 CYP3A4 (0.54) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL6559011 0.83 CYP3A4 (0.48) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL6764690 0.83 CYP3A4 (0.48) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL295315 0.82 CYP3A4 (0.47) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL19876727 0.81 CYP3A4 (0.50) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL7585383 0.81 CYP3A4 (0.50) CYP3A4TSHRTRPA1TDP1MAPK1
Dimethylamine SCHEMBL28015585 0.81 CYP3A4 (0.56) CYP3A4TSHRTRPA1TDP1MAPK1
SCHEMBL11317516 0.80 CYP3A4 (0.54) CYP3A4TSHRTRPA1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2680076-B1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK (JP) 2016-03-02 EP disclosed
EP-2680075-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2015-12-30 EP disclosed