SCHEMBL17370262

SCHEMBL17370262

C=CC(=O)Oc1ccc(C#Cc2c(OC(=O)C(=C)C)cc(C#Cc3ccc(OC(=O)C(=C)C)cc3)cc2OC(=O)C(=C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
THRB P10828 3/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
ACACB O00763 3/20 0.34
FFAR1 O14842 3/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
APP P05067 1/20 0.32
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17370266 0.99 ELANE (0.43) ELANETHRBKMT2AATMACACB
SCHEMBL17370575 0.95 ELANE (0.40) ELANETHRBKMT2AATMACACB
SCHEMBL17370576 0.95 ELANE (0.40) ELANETHRBKMT2AATMACACB
SCHEMBL17370573 0.95 ELANE (0.40) ELANETHRBKMT2AATMACACB
SCHEMBL17370571 0.95 ELANE (0.39) ELANETHRBKMT2AATMACACB
SCHEMBL17370741 0.93 ELANE (0.53) ELANETHRBKMT2AATMPOLB
SCHEMBL17370742 0.93 ELANE (0.53) ELANETHRBKMT2AATMPOLB
SCHEMBL17370735 0.93 ELANE (0.52) ELANETHRBKMT2AATMPOLB
SCHEMBL17370738 0.93 KMT2A (0.39) ELANETHRBKMT2AATMFFAR1
SCHEMBL17370739 0.92 ELANE (0.43) ELANETHRBKMT2AATMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9708534-B2 Polymerizable compound having triple bond, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-07-18 US disclosed
US-9708534-B2 Polymerizable compound having triple bond, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-07-18 US disclosed
US-20150376505-A1 POLYMERIZABLE COMPOUND HAVING TRIPLE BOND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-12-31 US disclosed
US-20150376505-A1 POLYMERIZABLE COMPOUND HAVING TRIPLE BOND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376505-A1 POLYMERIZABLE COMPOUND HAVING TRIPLE BOND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CCNT1, CCNA1, CCND1 ELANE 2133/4885THRB 4828/4885KMT2A 3636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.